Developmental expression of perlecan during murine embryogenesis

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Expression of the Heparan Sulfate Proteoglycan, Perlecan, during Mouse Embryogenesis and Perlecan Chondrogenic Activity In Vitro

Expression of the basement membrane heparan sulfate proteoglycan (HSPG), perlecan (Pln), mRNA, and protein has been examined during murine development. Both Pln mRNA and protein are highly expressed in cartilaginous regions of developing mouse embryos, but not in areas of membranous bone formation. Initially detected at low levels in precartilaginous areas of d 12.5 embryos, Pln protein accumul...

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ژورنال

عنوان ژورنال: Developmental Dynamics

سال: 1997

ISSN: 1058-8388,1097-0177

DOI: 10.1002/(sici)1097-0177(199710)210:2<130::aid-aja6>3.0.co;2-h